Imiquimod

Therapeutic classification: Drugs affecting the skin and mucous membranes> Miscellaneous agents affecting the skin and mucous membranes

– Safety response modulator

Activation of immune cells (with agonist effects of Tol-like receptor 7 (TLR-7))

Increased markers of cytokines and immune cells and their migration in the dermal application of the drug

Absorption: Partial (systemic absorption rate depending on the level of drug use)

Plasma peak: 12-9 hours

Excretion: Urine (less than 3% of the dose used)

Side effects of topical imiquimod:
Common complications (<10%):
Cutaneous: localized erythema, dry skin, flaky skin, cutaneous sclerosis, cutaneous ulcers, localized vesicles, peeling of the skin
Infectious: A fungal infection
Topical: local edema, discharge from the site, local itching, local burning
Respiratory: Infection of the upper respiratory tract
Relatively common side effects (10-1%):
Cardiovascular: Chest pain, localized pallor