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Indications for tamsulosin
Tamsulosin is used in prostate hyperplasia (prostate enlargement) (BPH).
Other uses of this drug: Treatment of symptoms of obstruction and dysfunction of the bladder outlet and facilitate the excretion of renal septa.
Mechanism of action of tamsulosin
Tamsulosin is an alpha 1A-adrenoceptor antagonist in the prostate. Involuntary muscles in the prostate are contracted by Alfa 1A adrenoceptors. Blockade of these receptors causes the involuntary muscles at the end of the bladder and prostate to relax and release, resulting in decreased urine flow and large prostate symptoms (BPH). Approximately 75% of alpha 1 prostate receptors are Alfa 1A.
Contraindications to the use of tamsulosin
This drug is strictly forbidden in pregnant women. Group X should be classified as copper, which leads to fetal organ failure.
Severe hypersensitivity to tamsulosin and similar compounds.
Side effects of tamsulosin
Common complications (<10%):
Cardiovascular: postural hypotension, symptomatic postural hypotension
Central nervous system: headache, dizziness
Genitourinary: Disorders of ejaculation
Infectious: Infection
Respiratory: rhinitis
Relatively common side effects (10-1%):
Central nervous system: drowsiness, insomnia, dizziness
Endocrinology and metabolism: Lack of libido
Gastrointestinal: diarrhea, nausea
Nervous, muscular and skeletal: weakness, back pain
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